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Living with SM impacts how individuals feel and function, going beyond what can be captured by objective measures or individual symptoms alone1,2
Everyday functioning in SM is not well correlated to objective measures of disease or specific individual symptoms,3 as the majority of patients experience diminished function1,2
Impact on daily life
Patients living with SM report that the unpredictable symptoms can disrupt their everyday life and lead to social withdrawal, anxiety and frustration.1,2 In the PRISM study, 65% of healthcare professionals (HCPs) perceived patients living with SM experience a negative impact on their daily life:4*
Impact on ability to work
43% of ISM and 82% of Advanced SM patients reported an impact on their ability to work, with 24% and 46%, respectively, reducing their working hours, and 10% and 22% voluntarily quitting their jobs4†
Symptom burden
Disability-adjusted life years (DALY) measure disease burden by the combining number of years of life lost due to premature death and disability caused by the disease5
ISM has a high multi-symptom burden, with estimated population DALYs comparable to those of common and serious conditions such as leukaemia or psoriasis5‡
Psychological impact
Patients with ISM report struggling to describe their symptoms, or feeling dismissed, which may lead to hesitation to share information and a delayed diagnosis1,2
Early recognition and referral to specialists are key to improving outcomes for patients living with SM6
Effective monitoring is essential for understanding the burden of disease and ultimately improving outcomes in your patients
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